With the recent release of Microsoft 2010 Betas it’s been quite the talk about making the leap to the 64-bit world. For SharePoint folks it’s also a question of compatibility. As of now, SharePoint 2010 Beta requires 64-bit SQL Server and either Windows Server 2008 or Windows 7. If you are running R2, then you are out of luck as Microsoft has not yet released a hotfix. Also, not to mention the escalated hardware requirements, specially memory-wise.
So if you wanna give it a try (myself included) here’s a nice write up by Jie Li that might come in handy with the planing and installation itself. Good Luck!